Thursday, August 11, 2011

Sizzix Big Shot - On The Edge - Mrna Processing and Metabolism: Methods and Protocols

Mrna Processing and Metabolism: Methods and Protocols

35219954
A collection of readily reproducible techniques for the study of mRNA processing and metabolism. These cutting-edge techniques range from cotranscriptional processing events that occur while the mNA is engaged with elongating RNA polymerase II, to in vivo and in vitro splicing and its biochemical analysis, and alternative splicing. Additional methods cover mRNA export, the recovery and analysis of mRNP complexes, cytoplasmic translation, mRNA degradation in vivo and in vitro, and the controversial concept of nuclear translation. Each proven protocol is described in step-by-step detail and contains a background introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding know pitfalls.

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Crime Patrol briefs some high-profile crimes, like Shivani Bhatnagar Murder Case, Nitish Katara Murder Case and rape and murder case of Priyadarshini Mattoo. How many of them gain justice? How many accused people involved in these heinous crimes go behind bars and get punished? Watch to find out.. CRIME PATROL is a reality series. However the case presentation would be a story telling form that would have the interest of a fiction drama presentation. The prelude and finale to the case would make the case a complete story. Interactions with the analysts on the show would be treated with the audience interest point of view keeping it only as much as essential to the story telling. Going beyond the drama of police action in a crime situation, the show also aims to look into the why behind a crime. Police action on one hand gives the show the edge of how the law keepers bring the culprits to book or stop a crime from being committed. On the other hand, the show will also be lo oking at the sociological aspect behind a crime- both from the victim as well as the criminals side. The cases would be driven by cameras moving along with the police force from the time a crime is reported or when the police receive a call till the point the case is brought to a logical conclusion in the police records for further movement in the court of law. As such the police force is deemed to be the law keeper and not the justice authority.

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